Finding. Early chaos in the nest rewires the nerve that talks to the heart. Panvini and Levitt use limited bedding, then watch vagally mediated heart-rate variability grow up. Females sprint then crash. Males start muted and catch up. Single-nucleus RNA from the vagal medulla splits the same way. Female neurons read out as mitochondrial dysfunction. Male neurons read out as mitochondrial adaptation. Spatial maps drop the female program in intermediate medulla and the loose nucleus ambiguus.
Score 79. First mouse HRV development series, sex, mitochondria, spatial. Confidence is medium until someone measures organelle function in those neurons.