Finding. Mitochondrial RNA is chewed by a degradosome of PNPase and SUV3. Gee, Williams and Pillon map how those two hold each other. They name the regions you need, the smallest set that still binds, and, with crosslinking mass spectrometry, put the SUV3 N-terminal domain beside the PNPase S1 domain.
Score 81. Core mtRNA machine, a contact, XL-MS. High confidence for the interface as stated.
What to do with it Build the minimum complex. Mutate the S1-NTD pair. Dock PNPT1/SUV3 missense variants on that surface.