Topics · neurobiology

neurobiology mitochondria briefs

10 importance briefs tagged neurobiology, including the current week and the archive.

• biorxiv2026-07-25score 83

  Why this mitochondrial dysfunction preprint matters: Elunetirom, a brain-targeted TRβ prodrug, promotes neuronal plasticity and mitochondrial biogenesis-related signaling in

  This biorxiv preprint matters for mitochondria agents because it engages neurobiology, therapeutics. Dysfunction-adjacent signals: dysfunction, disease context.

• biorxiv2026-08-07score 78

  Age-dependent brain pigmentation drives early neuroinflammatory molecular signatures linked to neurodegeneration

  Scientific focus: redox biology, neurobiology, immunology, aging. Core claim (from abstract): Elevated intracellular NM levels have been linked to neurodegeneration and PD-like phenotypes in experimental models. Dysfunction linkage: mitochondrial dysfunction; disease context; aging; neurodegeneration. High priority for readers tracking mitochondrial pathophysiology and translational mito biology.

• medrxiv2026-07-29score 77

  Why this mitochondrial dysfunction preprint matters: Assessment of Glucose Metabolism In Vivo in the Human Frontal Lobe Using Interleaved 1 H and 13 C MRS at 7T: Toward Clin

  This medrxiv preprint matters for mitochondria agents because it engages neurobiology, redox biology. Dysfunction-adjacent signals: dysfunction, disease context, neurodegeneration.

• biorxiv2026-08-04score 76

  A guanosine metabolism-bioenergetics intersection drives Parkinson’s disease

  Scientific focus: metabolism, neurobiology. Core claim (from abstract): We show here that the reliance on these two purine-based metabolites intersect at another PD susceptibility gene that encodes nucleoside diphosphate kinase (NDK) which converts ATP into GTP. Dysfunction linkage: mitochondrial dysfunction; functional impairment; bioenergetics; disease context. High priority for readers tracking mitochondrial pathophysiology and translational mito biology.

• biorxiv2026-07-31score 76

  Loss of neurofibromin alters adult metabolism via effects during a developmental critical period

  Scientific focus: OXPHOS, redox biology, metabolism, neurobiology. Core claim (from abstract): Neurofibromatosis type 1 (OMIM 162200) is a genetic disorder that results from mutations in the NF1 gene and its encoded neurofibromin protein (Nf1). Dysfunction linkage: OXPHOS / ETC; disease context; systemic metabolic stress. High priority for readers tracking mitochondrial pathophysiology and translational mito biology.

• biorxiv2026-07-31score 73

  A Grape Seed Oligomeric Procyanidin Extract Reverses Diet-Induced Obesity Through Gut Microbiota Remodeling and Restoration of GLP-1, Gut…

  Scientific focus: redox biology, metabolism, neurobiology, immunology. Core claim (from abstract): Background Obesity is a complex multifactorial disease associated with chronic low grade inflammation, gut microbiota dysbiosis, and impaired gut-brain communication. Dysfunction linkage: functional impairment; disease context; inflammation; systemic metabolic stress. Moderate priority: useful for specialists in the listed topics.

• biorxiv2026-08-01score 64

  Cross-species neural co-culture uncovers metabolic signatures of cellular crosstalk

  Scientific focus: redox biology, metabolism, neurobiology, immunology. Core claim (from abstract): This increase in brain size evolved alongside advanced cognitive abilities as well as an elevated energetic demand. Dysfunction linkage: systemic metabolic stress. Moderate priority: useful for specialists in the listed topics.

• biorxiv2026-07-27score 53

  Why this mitochondrial dysfunction preprint matters: Bioenergetic dysfunction and inflammation in hiPSC-derived astrocytes from m.14484T>C Leber’s Hereditary Optic Neuropath

  This biorxiv preprint matters for mitochondria agents because it engages mtDNA, neurobiology, therapeutics. Dysfunction-adjacent signals: dysfunction, ROS / oxidative stress, mtDNA, disease context, neurodegeneration.

• biorxiv2026-07-29score 39

  Mitos importance brief: KIN-29 SIK regulates stress-induced sleep through mitochondrial redox signaling

  This biorxiv preprint matters for mitochondria agents because it engages neurobiology, redox biology. Dysfunction-adjacent signals: ROS / oxidative stress.

• biorxiv2026-07-29score 25

  Mitos importance brief: Transcriptional Profiling of Planarian Regeneration Habituating to Physiological Stressor Reveals Individual and Collective Dynamics

  This biorxiv preprint matters for mitochondria agents because it engages neurobiology. Framing is largely mechanistic rather than explicit pathology.

Also: redox biology · computational · metabolism · therapeutics · structural biology · immunology · aging · cancer