Free for human readers
Mitochondria importance articles
Abstract-level scientific briefs on mitochondria preprints—structured for researchers and agents. Free in the browser. Machine JSON remains available via x402 for bots.
10 of 77 articles · updated 2026-08-08T16:01Z
- biorxiv2026-07-28score 83therapeuticsaging
Why this mitochondrial dysfunction preprint matters: Protein Phosphatase 2A Activation Attenuates Acute Myocardial Injury in Takotsubo Syndrome by Modulating Ferroptosis and
This biorxiv preprint matters for mitochondria agents because it engages therapeutics, aging. Dysfunction-adjacent signals: dysfunction, disease context.
Source preprint: Protein Phosphatase 2A Activation Attenuates Acute Myocardial Injury in Takotsubo Syndrome by Modulating Ferroptosis and Mitochondrial Injury in Cardiomyocytes
- medrxiv2026-07-30score 81mtDNAredox biologyaging
Why this mitochondrial dysfunction preprint matters: Data-Driven Biological Subtypes of Parkinson ′ s Disease
This medrxiv preprint matters for mitochondria agents because it engages mtDNA, redox biology, aging. Dysfunction-adjacent signals: dysfunction, mtDNA, disease context, neurodegeneration.
Source preprint: Data-Driven Biological Subtypes of Parkinson’s Disease
- biorxiv2026-08-07score 78redox biologyneurobiologyimmunology
Age-dependent brain pigmentation drives early neuroinflammatory molecular signatures linked to neurodegeneration
Scientific focus: redox biology, neurobiology, immunology, aging. Core claim (from abstract): Elevated intracellular NM levels have been linked to neurodegeneration and PD-like phenotypes in experimental models. Dysfunction linkage: mitochondrial dysfunction; disease context; aging; neurodegeneration. High priority for readers tracking mitochondrial pathophysiology and translational mito biology.
Source preprint: Age-dependent brain pigmentation drives early neuroinflammatory molecular signatures linked to neurodegeneration
- biorxiv2026-08-06score 69redox biologyagingcomputational
The ALS/FTD-linked protein CHCHD10 associates with the TDP-43 C-terminal domain through a CHCH-helix interface
Scientific focus: redox biology, aging, computational. Core claim (from abstract): CHCHD10 is a mitochondrial protein genetically and pathologically linked to TDP-43 dysfunction, but the molecular basis connecting both proteins has remained unclear. Dysfunction linkage: mitochondrial dysfunction; disease context; aging; neurodegeneration. Moderate priority: useful for specialists in the listed topics.
Source preprint: The ALS/FTD-linked protein CHCHD10 associates with the TDP-43 C-terminal domain through a CHCH-helix interface
- biorxiv2026-08-04score 67metabolismagingstructural biology
A single Omicron mutation reshapes ORF3a-driven host-cell remodelling
Scientific focus: metabolism, aging, structural biology, computational. Core claim (from abstract): Here, we combine complementary imaging approaches to define ORF3a function at nanometric scale, identifying underlying mechanisms, and determining how Omicron variant rewire this activity. Dysfunction linkage: aging; systemic metabolic stress. Moderate priority: useful for specialists in the listed topics.
Source preprint: A single Omicron mutation reshapes ORF3a-driven host-cell remodelling
- biorxiv2026-08-04score 66mitochondrial dynamicsredox biologymetabolism
Deep-ultraviolet microscopy reveals biomolecular spatiotemporal intracellular dynamics
Scientific focus: mitochondrial dynamics, redox biology, metabolism, aging. Core claim (from abstract): In this work, we demonstrate deep-ultraviolet (UV) microscopy as a powerful, label-free, high-resolution approach for quantifying multiscale intracellular dynamics with biomolecular specificity. Dysfunction linkage: disease context; aging; systemic metabolic stress. Moderate priority: useful for specialists in the listed topics.
Source preprint: Deep-ultraviolet microscopy reveals biomolecular spatiotemporal intracellular dynamics
- biorxiv2026-08-04score 64redox biologyimmunologyaging
Single-cell transcriptomics reveals a multiphasic Wolbachia host infection trajectory
Scientific focus: redox biology, immunology, aging, critical care. Core claim (from abstract): Here we used single-cell RNA sequencing to examine how w Mel colonization reshapes the host transcriptome during establishment of stable infection in D. melanogaster JW18 cell lines. Dysfunction linkage: aging. Moderate priority: useful for specialists in the listed topics.
Source preprint: Single-cell transcriptomics reveals a multiphasic Wolbachia host infection trajectory
- biorxiv2026-08-07score 60redox biologyagingstructural biology
QuantEM: An optimized platform of vision transformer-based models for segmentation and analysis of electron microscopy data
Scientific focus: redox biology, aging, structural biology, computational. Core claim (from abstract): Here we present QuantEM, an open-source platform for segmentation and analysis of EM data across imaging modalities, tissues, and species. Dysfunction linkage: aging. Moderate priority: useful for specialists in the listed topics.
Source preprint: QuantEM: An optimized platform of vision transformer-based models for segmentation and analysis of electron microscopy data
- biorxiv2026-08-04score 60redox biologyagingstructural biology
Physics-Guided Neural Reconstruction of Cellular Membranes for 3D Electron Microscopy
Scientific focus: redox biology, aging, structural biology. Core claim (from abstract): Modern advances in using neural networks to learn continuous implicit representations of complex shapes present a promising solution to this problem. Dysfunction linkage: aging. Moderate priority: useful for specialists in the listed topics.
Source preprint: Physics-Guided Neural Reconstruction of Cellular Membranes for 3D Electron Microscopy
- biorxiv2026-08-06score 25redox biologyaging
Mitos importance brief: Structural cell biology by mega-expansion microscopy
This biorxiv preprint matters for mitochondria agents because it engages redox biology, aging. Framing is largely mechanistic rather than explicit pathology.
Source preprint: Structural cell biology by mega-expansion microscopy