Topics · cardiovascular

cardiovascular mitochondria briefs

2 importance briefs tagged cardiovascular, including the current week and the archive.

• biorxiv2026-07-31score 82

  The SMYD1 p.Asn101Ser is a partial loss-of-function variant that impairs mitochondrial function and leads to early-onset cardiomyopathy

  Scientific focus: cardiovascular, structural biology, computational. Core claim (from abstract): Variants in SMYD1, a striated muscle-specific lysine methyltransferase critical for cardiac development and mitochondrial function, have only recently been linked to human cardiomyopathy. Dysfunction linkage: mitochondrial dysfunction; functional impairment; disease context. High priority for readers tracking mitochondrial pathophysiology and translational mito biology.

• biorxiv2026-08-01score 57

  Multicellular Programs Associated with Right Ventricular Adaptation in Pulmonary Arterial Hypertension

  Scientific focus: redox biology, cardiovascular, computational. Core claim (from abstract): Methods: We collected 32 human RV tissue biopsies from patients with idiopathic PAH, systemic sclerosis-associated PAH (SSc-PAH), systemic sclerosis without pulmonary hypertension, with 24 nonfailing donor RVs serving as controls. Dysfunction linkage: not strongly labeled in the abstract. Moderate priority: useful for specialists in the listed topics.

Also: redox biology · computational · metabolism · therapeutics · structural biology · immunology · aging · neurobiology